{"identifier":"/us/usc/t42/s18653","title_num":"42","num":"§ 18653.","heading":"Office of Science Biological Threat Preparedness Research Initiative","status":null,"guid":"idc060989b-3a70-11f1-ae07-e4213316b5fa","source_credit":"(Pub. L. 115–246, title III, § 315, as added Pub. L. 117–167, div. B, title I, § 10112(a), Aug. 9, 2022, 136 Stat. 1461.)","seq_in_title":8265,"parent_identifier":"/us/usc/t42/ch161/schIII","ancestors":[{"identifier":"/us/usc/t42","level":"title","num":"Title 42—","heading":"THE PUBLIC HEALTH AND WELFARE","status":null,"is_section":false},{"identifier":"/us/usc/t42/ch161","level":"chapter","num":"CHAPTER 161—","heading":"DEPARTMENT OF ENERGY RESEARCH AND INNOVATION","status":null,"is_section":false},{"identifier":"/us/usc/t42/ch161/schIII","level":"subchapter","num":"SUBCHAPTER III—","heading":"DEPARTMENT OF ENERGY OFFICE OF SCIENCE POLICY","status":null,"is_section":false}],"xml":"<section xmlns=\"http://xml.house.gov/schemas/uslm/1.0\" xmlns:xsi=\"http://www.w3.org/2001/XMLSchema-instance\" xmlns:dc=\"http://purl.org/dc/elements/1.1/\" xmlns:dcterms=\"http://purl.org/dc/terms/\" style=\"-uslm-lc:I80\" id=\"id1a1795c1-2957-11ed-8689-d724cb9b8ba1\" identifier=\"/us/usc/t42/s18653\"><num value=\"18653\">§ 18653.</num><heading> Office of Science Biological Threat Preparedness Research Initiative</heading><subsection style=\"-uslm-lc:I19\" class=\"indent2 firstIndent-2\" id=\"id1a1795c2-2957-11ed-8689-d724cb9b8ba1\" identifier=\"/us/usc/t42/s18653/a\"><num value=\"a\" class=\"bold\">(a)</num><heading class=\"bold\"> In general</heading><content><p style=\"-uslm-lc:I11\" class=\"indent0\">The Secretary shall establish within the Office of Science a cross-cutting research initiative, to be known as the “Biological Threat Preparedness Research Initiative”, to leverage the innovative analytical resources and tools, user facilities, and advanced computational and networking capabilities of the Department in order to support efforts that prevent, prepare for, predict, and respond to biological threats to national security, including infectious diseases.</p>\n</content>\n</subsection>\n<subsection style=\"-uslm-lc:I19\" class=\"indent2 firstIndent-2\" id=\"id1a1795c3-2957-11ed-8689-d724cb9b8ba1\" identifier=\"/us/usc/t42/s18653/b\"><num value=\"b\" class=\"bold\">(b)</num><heading class=\"bold\"> Competitive, merit-reviewed process</heading><content><p style=\"-uslm-lc:I11\" class=\"indent0\">The Secretary shall carry out the initiative established under subsection (a) through a competitive, merit-reviewed process, and consider applications from National Laboratories, institutions of higher education, multi-institutional collaborations, industry partners and other appropriate entities.</p>\n</content>\n</subsection>\n<subsection style=\"-uslm-lc:I19\" class=\"indent2 firstIndent-2\" id=\"id1a1795c4-2957-11ed-8689-d724cb9b8ba1\" identifier=\"/us/usc/t42/s18653/c\"><num value=\"c\" class=\"bold\">(c)</num><heading class=\"bold\"> Activities</heading><chapeau style=\"-uslm-lc:I11\" class=\"indent0\">In carrying out the initiative established under subsection (a), the Secretary shall—</chapeau><paragraph style=\"-uslm-lc:I12\" class=\"indent1\" id=\"id1a1795c5-2957-11ed-8689-d724cb9b8ba1\" identifier=\"/us/usc/t42/s18653/c/1\"><num value=\"1\">(1)</num><content> determine a comprehensive set of technical milestones for the research activities described in that subsection;</content>\n</paragraph>\n<paragraph style=\"-uslm-lc:I12\" class=\"indent1\" id=\"id1a1795c6-2957-11ed-8689-d724cb9b8ba1\" identifier=\"/us/usc/t42/s18653/c/2\"><num value=\"2\">(2)</num><chapeau> prioritize the objectives of—</chapeau><subparagraph style=\"-uslm-lc:I13\" class=\"indent2\" id=\"id1a1795c7-2957-11ed-8689-d724cb9b8ba1\" identifier=\"/us/usc/t42/s18653/c/2/A\"><num value=\"A\">(A)</num><content> supporting fundamental research and development in advanced analytics, experimental studies, materials synthesis, and high-performance computing technologies needed in order to more quickly and effectively characterize, model, simulate, and predict complex natural phenomena and biological materials related to emerging biological threats;</content>\n</subparagraph>\n<subparagraph style=\"-uslm-lc:I13\" class=\"indent2\" id=\"id1a1795c8-2957-11ed-8689-d724cb9b8ba1\" identifier=\"/us/usc/t42/s18653/c/2/B\"><num value=\"B\">(B)</num><content> supporting the development of tools that inform epidemiological modeling, and applying artificial intelligence, machine learning, and other computing tools to accelerate such processes;</content>\n</subparagraph>\n<subparagraph style=\"-uslm-lc:I13\" class=\"indent2\" id=\"id1a1795c9-2957-11ed-8689-d724cb9b8ba1\" identifier=\"/us/usc/t42/s18653/c/2/C\"><num value=\"C\">(C)</num><content> supporting research and capabilities that enhance understanding and modeling of the transport of pathogens in indoor and outdoor air and water environments;</content>\n</subparagraph>\n<subparagraph style=\"-uslm-lc:I13\" class=\"indent2\" id=\"id1a1795ca-2957-11ed-8689-d724cb9b8ba1\" identifier=\"/us/usc/t42/s18653/c/2/D\"><num value=\"D\">(D)</num><content> identifying priority research opportunities and capabilities for molecular design and modeling for medical countermeasures;</content>\n</subparagraph>\n<subparagraph style=\"-uslm-lc:I13\" class=\"indent2\" id=\"id1a17bbdb-2957-11ed-8689-d724cb9b8ba1\" identifier=\"/us/usc/t42/s18653/c/2/E\"><num value=\"E\">(E)</num><content> ensuring that new experimental and computational tools are accessible to relevant research communities, including private sector entities and other Federal research institutions; and</content>\n</subparagraph>\n<subparagraph style=\"-uslm-lc:I13\" class=\"indent2\" id=\"id1a17bbdc-2957-11ed-8689-d724cb9b8ba1\" identifier=\"/us/usc/t42/s18653/c/2/F\"><num value=\"F\">(F)</num><content> supporting activities and projects that combine computational modeling and simulation with experimental research facilities and studies;</content>\n</subparagraph>\n</paragraph>\n<paragraph style=\"-uslm-lc:I12\" class=\"indent1\" id=\"id1a17bbdd-2957-11ed-8689-d724cb9b8ba1\" identifier=\"/us/usc/t42/s18653/c/3\"><num value=\"3\">(3)</num><content> leverage the research infrastructure of the Department, including scientific computing user facilities, x-ray light sources, neutron scattering facilities, nanoscale science research centers, and sequencing and biocharacterization facilities;</content>\n</paragraph>\n<paragraph style=\"-uslm-lc:I12\" class=\"indent1\" id=\"id1a17bbde-2957-11ed-8689-d724cb9b8ba1\" identifier=\"/us/usc/t42/s18653/c/4\"><num value=\"4\">(4)</num><content> leverage experience from existing modeling and simulation research and work sponsored by the Department and promote collaboration and data sharing between National Laboratories, research entities, and user facilities of the Department by providing necessary access and secure data transfer capabilities; and</content>\n</paragraph>\n<paragraph style=\"-uslm-lc:I12\" class=\"indent1\" id=\"id1a17bbdf-2957-11ed-8689-d724cb9b8ba1\" identifier=\"/us/usc/t42/s18653/c/5\"><num value=\"5\">(5)</num><content> ensure that new experimental and computational tools are accessible to relevant research communities, including private sector entities, to address emerging biological threats.</content>\n</paragraph>\n</subsection>\n<subsection style=\"-uslm-lc:I19\" class=\"indent2 firstIndent-2\" id=\"id1a17bbe0-2957-11ed-8689-d724cb9b8ba1\" identifier=\"/us/usc/t42/s18653/d\"><num value=\"d\" class=\"bold\">(d)</num><heading class=\"bold\"> Coordination</heading><chapeau style=\"-uslm-lc:I11\" class=\"indent0\">In carrying out the initiative established under subsection (a), the Secretary shall coordinate activities with—</chapeau><paragraph style=\"-uslm-lc:I12\" class=\"indent1\" id=\"id1a17bbe1-2957-11ed-8689-d724cb9b8ba1\" identifier=\"/us/usc/t42/s18653/d/1\"><num value=\"1\">(1)</num><content> other relevant offices of the Department;</content>\n</paragraph>\n<paragraph style=\"-uslm-lc:I12\" class=\"indent1\" id=\"id1a17bbe2-2957-11ed-8689-d724cb9b8ba1\" identifier=\"/us/usc/t42/s18653/d/2\"><num value=\"2\">(2)</num><content> the National Nuclear Security Administration;</content>\n</paragraph>\n<paragraph style=\"-uslm-lc:I12\" class=\"indent1\" id=\"id1a17bbe3-2957-11ed-8689-d724cb9b8ba1\" identifier=\"/us/usc/t42/s18653/d/3\"><num value=\"3\">(3)</num><content> the National Laboratories;</content>\n</paragraph>\n<paragraph style=\"-uslm-lc:I12\" class=\"indent1\" id=\"id1a17bbe4-2957-11ed-8689-d724cb9b8ba1\" identifier=\"/us/usc/t42/s18653/d/4\"><num value=\"4\">(4)</num><content> the Director of the National Science Foundation;</content>\n</paragraph>\n<paragraph style=\"-uslm-lc:I12\" class=\"indent1\" id=\"id1a17bbe5-2957-11ed-8689-d724cb9b8ba1\" identifier=\"/us/usc/t42/s18653/d/5\"><num value=\"5\">(5)</num><content> the Director of the Centers for Disease Control and Prevention;</content>\n</paragraph>\n<paragraph style=\"-uslm-lc:I12\" class=\"indent1\" id=\"id1a17bbe6-2957-11ed-8689-d724cb9b8ba1\" identifier=\"/us/usc/t42/s18653/d/6\"><num value=\"6\">(6)</num><content> the Director of the National Institutes of Health;</content>\n</paragraph>\n<paragraph style=\"-uslm-lc:I12\" class=\"indent1\" id=\"id1a17bbe7-2957-11ed-8689-d724cb9b8ba1\" identifier=\"/us/usc/t42/s18653/d/7\"><num value=\"7\">(7)</num><content> the Assistant Secretary for Preparedness and Response;</content>\n</paragraph>\n<paragraph style=\"-uslm-lc:I12\" class=\"indent1\" id=\"id1a17bbe8-2957-11ed-8689-d724cb9b8ba1\" identifier=\"/us/usc/t42/s18653/d/8\"><num value=\"8\">(8)</num><content> the heads of other relevant Federal agencies;</content>\n</paragraph>\n<paragraph style=\"-uslm-lc:I12\" class=\"indent1\" id=\"id1a17bbe9-2957-11ed-8689-d724cb9b8ba1\" identifier=\"/us/usc/t42/s18653/d/9\"><num value=\"9\">(9)</num><content> institutions of higher education; and</content>\n</paragraph>\n<paragraph style=\"-uslm-lc:I12\" class=\"indent1\" id=\"id1a17bbea-2957-11ed-8689-d724cb9b8ba1\" identifier=\"/us/usc/t42/s18653/d/10\"><num value=\"10\">(10)</num><content> the private sector.</content>\n</paragraph>\n</subsection>\n<subsection style=\"-uslm-lc:I19\" class=\"indent2 firstIndent-2\" id=\"id1a17bbeb-2957-11ed-8689-d724cb9b8ba1\" identifier=\"/us/usc/t42/s18653/e\"><num value=\"e\" class=\"bold\">(e)</num><heading class=\"bold\"> Infectious Diseases High Performance Computing Research Consortium</heading><paragraph style=\"-uslm-lc:I79\" class=\"indent3 firstIndent-2\" id=\"id1a17bbec-2957-11ed-8689-d724cb9b8ba1\" identifier=\"/us/usc/t42/s18653/e/1\"><num value=\"1\" class=\"bold\">(1)</num><heading class=\"bold\"> In general</heading><content><p style=\"-uslm-lc:I12\" class=\"indent1\">The Secretary, in coordination with the Director of the National Science Foundation and the Director of the Office of Science and Technology Policy, shall establish and operate an Emerging Infectious Diseases High Performance Computing Research Consortium (referred to in this section as the “Consortium”), to support the initiative established under subsection (a) by providing, to the extent practicable, a centralized entity for multidisciplinary, collaborative, emerging infectious disease and biosecurity research and development through high performance computing and advanced data analytics technologies and processes, in conjunction with the experimental research facilities and studies supported by the Department.</p>\n</content>\n</paragraph>\n<paragraph style=\"-uslm-lc:I79\" class=\"indent3 firstIndent-2\" id=\"id1a17e2fd-2957-11ed-8689-d724cb9b8ba1\" identifier=\"/us/usc/t42/s18653/e/2\"><num value=\"2\" class=\"bold\">(2)</num><heading class=\"bold\"> Membership</heading><content><p style=\"-uslm-lc:I12\" class=\"indent1\">The members of the Consortium may include representatives from relevant Federal agencies, the National Laboratories, the private sector, and institutions of higher education, which can each contribute relevant compute time, capabilities, or other resources.</p>\n</content>\n</paragraph>\n<paragraph style=\"-uslm-lc:I79\" class=\"indent3 firstIndent-2\" id=\"id1a17e2fe-2957-11ed-8689-d724cb9b8ba1\" identifier=\"/us/usc/t42/s18653/e/3\"><num value=\"3\" class=\"bold\">(3)</num><heading class=\"bold\"> Activities</heading><chapeau style=\"-uslm-lc:I12\" class=\"indent1\">The Consortium shall—</chapeau><subparagraph style=\"-uslm-lc:I13\" class=\"indent2\" id=\"id1a17e2ff-2957-11ed-8689-d724cb9b8ba1\" identifier=\"/us/usc/t42/s18653/e/3/A\"><num value=\"A\">(A)</num><content> match applicants with available Federal and private sector computing resources;</content>\n</subparagraph>\n<subparagraph style=\"-uslm-lc:I13\" class=\"indent2\" id=\"id1a17e300-2957-11ed-8689-d724cb9b8ba1\" identifier=\"/us/usc/t42/s18653/e/3/B\"><num value=\"B\">(B)</num><content> consider supplemental awards for computing partnerships with Consortium members to qualifying entities on a competitive merit-review basis;</content>\n</subparagraph>\n<subparagraph style=\"-uslm-lc:I13\" class=\"indent2\" id=\"id1a17e301-2957-11ed-8689-d724cb9b8ba1\" identifier=\"/us/usc/t42/s18653/e/3/C\"><num value=\"C\">(C)</num><content> encourage collaboration and communication among member representatives of the Consortium and awardees;</content>\n</subparagraph>\n<subparagraph style=\"-uslm-lc:I13\" class=\"indent2\" id=\"id1a17e302-2957-11ed-8689-d724cb9b8ba1\" identifier=\"/us/usc/t42/s18653/e/3/D\"><num value=\"D\">(D)</num><content> provide access to the high-performance computing capabilities, expertise, and user facilities of the Department and the National Laboratories; and</content>\n</subparagraph>\n<subparagraph style=\"-uslm-lc:I13\" class=\"indent2\" id=\"id1a17e303-2957-11ed-8689-d724cb9b8ba1\" identifier=\"/us/usc/t42/s18653/e/3/E\"><num value=\"E\">(E)</num><chapeau> submit an annual report to the Secretary summarizing the activities of the Consortium, including—</chapeau><clause style=\"-uslm-lc:I14\" class=\"indent3\" id=\"id1a17e304-2957-11ed-8689-d724cb9b8ba1\" identifier=\"/us/usc/t42/s18653/e/3/E/i\"><num value=\"i\">(i)</num><content> describing each project undertaken by the Consortium;</content>\n</clause>\n<clause style=\"-uslm-lc:I14\" class=\"indent3\" id=\"id1a17e305-2957-11ed-8689-d724cb9b8ba1\" identifier=\"/us/usc/t42/s18653/e/3/E/ii\"><num value=\"ii\">(ii)</num><content> detailing organizational expenditures; and</content>\n</clause>\n<clause style=\"-uslm-lc:I14\" class=\"indent3\" id=\"id1a17e306-2957-11ed-8689-d724cb9b8ba1\" identifier=\"/us/usc/t42/s18653/e/3/E/iii\"><num value=\"iii\">(iii)</num><content> evaluating contributions to the achievement of technical milestones as determined in subsection (a).</content>\n</clause>\n</subparagraph>\n</paragraph>\n<paragraph style=\"-uslm-lc:I79\" class=\"indent3 firstIndent-2\" id=\"id1a17e307-2957-11ed-8689-d724cb9b8ba1\" identifier=\"/us/usc/t42/s18653/e/4\"><num value=\"4\" class=\"bold\">(4)</num><heading class=\"bold\"> Coordination</heading><content><p style=\"-uslm-lc:I12\" class=\"indent1\">The Secretary shall ensure the coordination of, and avoid unnecessary duplication of, the activities of the Consortium with the activities of other research entities of the Department, other Federal research institutions, institutions of higher education, and the private sector.</p>\n</content>\n</paragraph>\n</subsection>\n<subsection style=\"-uslm-lc:I19\" class=\"indent2 firstIndent-2\" id=\"id1a17e308-2957-11ed-8689-d724cb9b8ba1\" identifier=\"/us/usc/t42/s18653/f\"><num value=\"f\" class=\"bold\">(f)</num><heading class=\"bold\"> Report</heading><chapeau style=\"-uslm-lc:I11\" class=\"indent0\">Not later than 2 years after <date date=\"2022-08-09\">August 9, 2022</date>, the Secretary shall submit to the Committee on Science, Space, and Technology and the Committee on Energy and Commerce of the House of Representatives, and the Committee on Energy and Natural Resources, the Committee on Commerce, Science, and Transportation, and the Committee on Health, Education, Labor, and Pensions of the Senate, a report detailing the effectiveness of—</chapeau><paragraph style=\"-uslm-lc:I12\" class=\"indent1\" id=\"id1a180a19-2957-11ed-8689-d724cb9b8ba1\" identifier=\"/us/usc/t42/s18653/f/1\"><num value=\"1\">(1)</num><content> the interagency coordination among each Federal agency involved in the initiative established under subsection (a);</content>\n</paragraph>\n<paragraph style=\"-uslm-lc:I12\" class=\"indent1\" id=\"id1a180a1a-2957-11ed-8689-d724cb9b8ba1\" identifier=\"/us/usc/t42/s18653/f/2\"><num value=\"2\">(2)</num><content> the collaborative research achievements of that initiative, including the achievement of the technical milestones determined under that subsection; and</content>\n</paragraph>\n<paragraph style=\"-uslm-lc:I12\" class=\"indent1\" id=\"id1a180a1b-2957-11ed-8689-d724cb9b8ba1\" identifier=\"/us/usc/t42/s18653/f/3\"><num value=\"3\">(3)</num><content> potential opportunities to expand the technical capabilities of the Department.</content>\n</paragraph>\n</subsection>\n<subsection style=\"-uslm-lc:I19\" class=\"indent2 firstIndent-2\" id=\"id1a180a1c-2957-11ed-8689-d724cb9b8ba1\" identifier=\"/us/usc/t42/s18653/g\"><num value=\"g\" class=\"bold\">(g)</num><heading class=\"bold\"> Funding</heading><content><p style=\"-uslm-lc:I11\" class=\"indent0\">Out of funds authorized to be appropriated for the Office of Science in a fiscal year, there is authorized to be appropriated to the Secretary to carry out the activities under this section $50,000,000 for each of fiscal years 2023 through 2027.</p>\n</content>\n</subsection>\n<sourceCredit id=\"id1a180a1d-2957-11ed-8689-d724cb9b8ba1\">(<ref href=\"/us/pl/115/246/tIII/s315\">Pub. L. 115–246, title III, § 315</ref>, as added <ref href=\"/us/pl/117/167/dB/tI/s10112/a\">Pub. L. 117–167, div. B, title I, § 10112(a)</ref>, <date date=\"2022-08-09\">Aug. 9, 2022</date>, <ref href=\"/us/stat/136/1461\">136 Stat. 1461</ref>.)</sourceCredit>\n</section>","provision":null,"duplicates":[],"release":{"label":"119-83","currency_date":"2026-04-13","congress":119,"law_num":83,"excluded_laws":[],"update_num":null,"seq":371,"is_partial":false,"caveat":null,"titles_affected":["01","02","05","06","07","08","10","11","12","15","16","18","19","20","21","22","23","26","28","29","30","31","33","34","36","38","40","41","42","43","48","49","50","51","54"],"ingested_titles":[]},"served_from":{"label":"119-83","currency_date":"2026-04-13","congress":119,"law_num":83,"excluded_laws":[],"update_num":null,"seq":371,"is_partial":false,"caveat":null,"titles_affected":["01","02","05","06","07","08","10","11","12","15","16","18","19","20","21","22","23","26","28","29","30","31","33","34","36","38","40","41","42","43","48","49","50","51","54"],"ingested_titles":[]},"content_first_seen":{"label":"117-174not169","currency_date":"2022-08-26","congress":117,"law_num":174,"excluded_laws":[169],"update_num":null,"seq":283,"is_partial":true,"caveat":"Current through Public Law 117-174 (08/26/2022), except 117-169.","titles_affected":["02","06","15","26","33","34","38","40","41","42","44","47","51"],"ingested_titles":[]},"is_exact":true,"note":null}