<section xmlns="http://xml.house.gov/schemas/uslm/1.0" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" style="-uslm-lc:I80" id="ida4a02c71-09a0-11eb-a85b-f5cef3d06f4d" identifier="/us/usc/t42/s283e"><num value="283e">§ 283e.</num><heading> Plan for use of animals in research</heading><subsection style="-uslm-lc:I19" class="indent2 firstIndent-2" id="ida4a02c72-09a0-11eb-a85b-f5cef3d06f4d" identifier="/us/usc/t42/s283e/a"><num value="a" class="bold">(a)</num><heading class="bold"> Preparation</heading><chapeau style="-uslm-lc:I11" class="indent0">The Director of NIH, after consultation with the committee established under subsection (e), shall prepare a plan—</chapeau><paragraph style="-uslm-lc:I12" class="indent1" id="ida4a02c73-09a0-11eb-a85b-f5cef3d06f4d" identifier="/us/usc/t42/s283e/a/1"><num value="1">(1)</num><chapeau> for the National Institutes of Health to conduct or support research into—</chapeau><subparagraph style="-uslm-lc:I13" class="indent2" id="ida4a02c74-09a0-11eb-a85b-f5cef3d06f4d" identifier="/us/usc/t42/s283e/a/1/A"><num value="A">(A)</num><content> methods of biomedical research and experimentation that do not require the use of animals;</content>
</subparagraph>
<subparagraph style="-uslm-lc:I13" class="indent2" id="ida4a02c75-09a0-11eb-a85b-f5cef3d06f4d" identifier="/us/usc/t42/s283e/a/1/B"><num value="B">(B)</num><content> methods of such research and experimentation that reduce the number of animals used in such research;</content>
</subparagraph>
<subparagraph style="-uslm-lc:I13" class="indent2" id="ida4a02c76-09a0-11eb-a85b-f5cef3d06f4d" identifier="/us/usc/t42/s283e/a/1/C"><num value="C">(C)</num><content> methods of such research and experimentation that produce less pain and distress in such animals; and</content>
</subparagraph>
<subparagraph style="-uslm-lc:I13" class="indent2" id="ida4a02c77-09a0-11eb-a85b-f5cef3d06f4d" identifier="/us/usc/t42/s283e/a/1/D"><num value="D">(D)</num><content> methods of such research and experimentation that involve the use of marine life (other than marine mammals);</content>
</subparagraph>
</paragraph>
<paragraph style="-uslm-lc:I12" class="indent1" id="ida4a02c78-09a0-11eb-a85b-f5cef3d06f4d" identifier="/us/usc/t42/s283e/a/2"><num value="2">(2)</num><content> for establishing the validity and reliability of the methods described in paragraph (1);</content>
</paragraph>
<paragraph style="-uslm-lc:I12" class="indent1" id="ida4a02c79-09a0-11eb-a85b-f5cef3d06f4d" identifier="/us/usc/t42/s283e/a/3"><num value="3">(3)</num><content> for encouraging the acceptance by the scientific community of such methods that have been found to be valid and reliable; and</content>
</paragraph>
<paragraph style="-uslm-lc:I12" class="indent1" id="ida4a02c7a-09a0-11eb-a85b-f5cef3d06f4d" identifier="/us/usc/t42/s283e/a/4"><num value="4">(4)</num><content> for training scientists in the use of such methods that have been found to be valid and reliable.</content>
</paragraph>
</subsection>
<subsection style="-uslm-lc:I19" class="indent2 firstIndent-2" id="ida4a02c7b-09a0-11eb-a85b-f5cef3d06f4d" identifier="/us/usc/t42/s283e/b"><num value="b" class="bold">(b)</num><heading class="bold"> Submission to Congressional committees</heading><content><p style="-uslm-lc:I11" class="indent0">Not later than <date date="1993-10-01">October 1, 1993</date>, the Director of NIH shall submit to the Committee on Energy and Commerce of the House of Representatives, and to the Committee on Labor and Human Resources of the Senate, the plan required in subsection (a) and shall begin implementation of the plan.</p>
</content>
</subsection>
<subsection style="-uslm-lc:I19" class="indent2 firstIndent-2" id="ida4a02c7c-09a0-11eb-a85b-f5cef3d06f4d" identifier="/us/usc/t42/s283e/c"><num value="c" class="bold">(c)</num><heading class="bold"> Periodic review and revision</heading><content><p style="-uslm-lc:I11" class="indent0">The Director of NIH shall periodically review, and as appropriate, make revisions in the plan required under subsection (a). A description of any revision made in the plan shall be included in the first biennial report under <ref href="/us/usc/t42/s283">section 283 of this title</ref> that is submitted after the revision is made.</p>
</content>
</subsection>
<subsection style="-uslm-lc:I19" class="indent2 firstIndent-2" id="ida4a02c7d-09a0-11eb-a85b-f5cef3d06f4d" identifier="/us/usc/t42/s283e/d"><num value="d" class="bold">(d)</num><heading class="bold"> Dissemination of information</heading><content><p style="-uslm-lc:I11" class="indent0">The Director of NIH shall take such actions as may be appropriate to convey to scientists and others who use animals in biomedical or behavioral research or experimentation information respecting the methods found to be valid and reliable under subsection (a)(2).</p>
</content>
</subsection>
<subsection style="-uslm-lc:I19" class="indent2 firstIndent-2" id="ida4a0538e-09a0-11eb-a85b-f5cef3d06f4d" identifier="/us/usc/t42/s283e/e"><num value="e" class="bold">(e)</num><heading class="bold"> Interagency Coordinating Committee on the Use of Animals in Research</heading><paragraph style="-uslm-lc:I11" class="indent0" id="ida4a0538f-09a0-11eb-a85b-f5cef3d06f4d" identifier="/us/usc/t42/s283e/e/1"><num value="1">(1)</num><content> The Director of NIH shall establish within the National Institutes of Health a committee to be known as the Interagency Coordinating Committee on the Use of Animals in Research (in this subsection referred to as the “Committee”).</content>
</paragraph>
<paragraph style="-uslm-lc:I11" class="indent0" id="ida4a05390-09a0-11eb-a85b-f5cef3d06f4d" identifier="/us/usc/t42/s283e/e/2"><num value="2">(2)</num><content> The Committee shall provide advice to the Director of NIH on the preparation of the plan required in subsection (a).</content>
</paragraph>
<paragraph style="-uslm-lc:I11" class="indent0" id="ida4a05391-09a0-11eb-a85b-f5cef3d06f4d" identifier="/us/usc/t42/s283e/e/3"><num value="3">(3)</num><chapeau> The Committee shall be composed of—</chapeau><subparagraph style="-uslm-lc:I12" class="indent1" id="ida4a05392-09a0-11eb-a85b-f5cef3d06f4d" identifier="/us/usc/t42/s283e/e/3/A"><num value="A">(A)</num><content> the Directors of each of the national research institutes (or the designees of such Directors); and</content>
</subparagraph>
<subparagraph style="-uslm-lc:I12" class="indent1" id="ida4a05393-09a0-11eb-a85b-f5cef3d06f4d" identifier="/us/usc/t42/s283e/e/3/B"><num value="B">(B)</num><content> representatives of the Environmental Protection Agency, the Food and Drug Administration, the Consumer Product Safety Commission, the National Science Foundation, and such additional agencies as the Director of NIH determines to be appropriate, which representatives shall include not less than one veterinarian with expertise in laboratory-animal medicine.</content>
</subparagraph>
</paragraph>
</subsection>
<sourceCredit id="ida4a05394-09a0-11eb-a85b-f5cef3d06f4d">(<ref href="/us/act/1944-07-01/ch373">July 1, 1944, ch. 373</ref>, title IV, § 404C, as added <ref href="/us/pl/103/43/tII/s205/a">Pub. L. 103–43, title II, § 205(a)</ref>, <date date="1993-06-10">June 10, 1993</date>, <ref href="/us/stat/107/146">107 Stat. 146</ref>; amended <ref href="/us/pl/112/74/dF/tII/s221/d/2">Pub. L. 112–74, div. F, title II, § 221(d)(2)</ref>, <date date="2011-12-23">Dec. 23, 2011</date>, <ref href="/us/stat/125/1090">125 Stat. 1090</ref>.)</sourceCredit>
<notes type="uscNote" id="ida4a05395-09a0-11eb-a85b-f5cef3d06f4d">
<note style="-uslm-lc:I74" topic="amendments" id="ida4a05396-09a0-11eb-a85b-f5cef3d06f4d"><heading class="centered smallCaps">Amendments</heading><p style="-uslm-lc:I21" class="indent0">2011—Subsec. (e)(3)(A). <ref href="/us/pl/112/74">Pub. L. 112–74</ref> struck out “and the Director of the Center for Research Resources” after “institutes”.</p>
</note>
<note style="-uslm-lc:I78" topic="changeOfName" id="ida4a05397-09a0-11eb-a85b-f5cef3d06f4d">
<heading class="centered smallCaps">Change of Name</heading>
<p style="-uslm-lc:I21" class="indent0">Committee on Labor and Human Resources of Senate changed to Committee on Health, Education, Labor, and Pensions of Senate by Senate Resolution No. 20, One Hundred Sixth Congress, <date date="1999-01-19">Jan. 19, 1999</date>.</p>
<p style="-uslm-lc:I21" class="indent0">Committee on Energy and Commerce of House of Representatives treated as referring to Committee on Commerce of House of Representatives by <ref href="/us/pl/104/14/s1/a">section 1(a) of Pub. L. 104–14</ref>, set out as a note preceding <ref href="/us/usc/t2/s21">section 21 of Title 2</ref>, The Congress. Committee on Commerce of House of Representatives changed to Committee on Energy and Commerce of House of Representatives, and jurisdiction over matters relating to securities and exchanges and insurance generally transferred to Committee on Financial Services of House of Representatives by House Resolution No. 5, One Hundred Seventh Congress, <date date="2001-01-03">Jan. 3, 2001</date>.</p>
</note>
</notes>
</section>